Mental Health Support

Vegetables and fruits such as celery, parsley, broccoli, onion leaves, carrots, peppers, cabbages, apple skins, and chrysanthemum flowers are luteolin rich [4,10-13]. Plants rich in luteolin have been used as Chinese traditional medicine for hypertension, inflammatory diseases, and cancer [1]. The pharmacological activities of luteolin could be functionally related to each other. For instance, the anti-inflammatory effect of luteolin also may be linked to its anticancer function. The anticancer property of luteolin is associated with inducing apoptosis, which involves redox regulation, DNA damage, and protein kinases in inhibiting proliferation of cancer cells and suppressing metastasis and angiogenesis. Furthermore, luteolin sensitizes a variety of cancer cells to therapeutically induced cytotoxicity through suppressing cell survival pathways and stimulating apoptosis pathways. Notably, luteolin is blood-brain barrier permeable, rendering it applicable to the therapy of central nerve system diseases, including brain cancer [14]. Furthermore, recent studies have attributed a cancer prevention potential to luteolin.