Bacteria Frozen Inside 5,000-Year-Old Ice Cave Is Crazy Resistant to Antibiotics [View all]

Source: Gizmodo

A study published Tuesday in the journal Frontiers in Microbiology describes Psychrobacter SC65A.3, a bacterial strain discovered frozen inside 5,000-year-old layers of cave ice in Romania. Testing revealed that SC65A.3 is resistant to 10 modern antibiotics and carries more than 100 genes linked to resistance despite never being exposed to these drugs.

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While exposure to antibiotics amplifies the prevalence of resistance genes, it does not imbue microbes with these protective traits. Those arise naturally through random genetic mutations and the constant pressure to out-perform other microorganisms in the environment, many of which produce their own antimicrobial compounds.

The ancient Psychrobacter SC65A.3 strain is a perfect example of how these natural processes lead to antibiotic resistance. Purcarea and her colleagues found it inside an 82-foot (25-meter) ice core they extracted from Scarisoara Ice Cave in northwestern Romania. The core represents 13,000 years of climatic history, including the 5,000-year-old ice layers that contained SC65A.3.

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“If melting ice releases these microbes, these genes could spread to modern bacteria, adding to the global challenge of antibiotic resistance,” Purcarea said. As the global temperature rises, the risk of releasing ancient superbugs into the environment grows. Studying these bacterial strains, however, can also lead to the discovery of unique enzymes and antimicrobial compounds that inspire new drugs and other biotechnological innovations, Purcarea noted.

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Read more: https://gizmodo.com/bacteria-frozen-inside-5000-year-old-ice-cave-is-crazy-resistant-to-antibiotics-2000723002