The maximum number of US Senate seats the Democrats will end up with after 2022 is 57.

57)IA(Finkenauer-D or Franken-D could portray Grassley-R as an old career politician.)IA is like what MO was in the 2010’s.
56)MO(Busch Valentine-D or Kunce-D vs Greitens-R) Greitens as the Republican nominee gives Democrats a fighting chance to win back a US Senate seat from MO.
55)FL(Demings-D)
54)OH(Ryan-D)
53)NC(Beasley-D)
52)WI(Barnes-D)
51)GA(Warnock-D)
50)PA(Fetterman-D or Lamb-D)
49)AZ(Kelly-D)
48)NV(Cortez Masto-D)
47)NH(Hassan-D)
46)CO(Bennet-D)
45)WA(Murray-D)
44)IL(Duckworth-D)
43)OR(Wyden-D)
42)VT(Welch-D)
41)CT(Blumenthal-D)
40)MD(Van Hollen-D)
39)CA(Padilla-D)
38)NY(Schumer-D)
37)HI(Schatz-D)