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Celerity

(55,176 posts)
Wed Jun 10, 2026, 03:18 AM 19 hrs ago

Vaccine made by AI will shield against mutations


The breakthrough at Cambridge paves the way for protection against viruses that have not even evolved

https://www.thetimes.com/uk/science/article/vaccine-ai-future-proof-mutations-0jkqq60kc

https://archive.ph/x3Wfq


Alamy

A vaccine that can protect against future mutations of viruses has been designed using artificial intelligence and trialled in humans for the first time, University of Cambridge researchers have announced. It paves the way for the development of “universal vaccines” that could protect against a wide range of variants of a particular family of viruses such as Ebola or coronaviruses, including those that have not yet evolved and emerged, academics have said.

Scientists at the university have announced “the first human clinical trial of a universal Sarbeco coronavirus vaccine”, referring to a group that includes Covid-causing viruses. In an early phase-one trial of 39 people to assess the safety of the vaccine, researchers found no significant side-effects.

The vaccine not only triggered immune responses to SARS-CoV-2, the virus behind Covid-19, and Sars, but also to a related group of bat viruses that may jump to humans in future. A second trial, of 200 people, will focus on the strength of the immune response the vaccine can produce.


A volunteer receives the trial vaccine at Cambridge University

A Cambridge University spokesman said: “This trial proves the safety of an entirely new way of designing vaccines. The technology uses an AI-designed ‘super-antigen’ to provide lasting protection against a broad range of viruses … even as they mutate. “Vaccines developed in this way could protect against future emerging virus threats. The technology also reduces the need for frequent reformulation.”

No more ‘tail-chasing’.............................

snip
16 replies = new reply since forum marked as read
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Vaccine made by AI will shield against mutations (Original Post) Celerity 19 hrs ago OP
Cool! I'd volunteer, too! QueerDuck 16 hrs ago #1
As someone who gets colds that last 3 weeks, I'm hoping this works EdmondDantes_ 14 hrs ago #2
And now anti-vax AI cheerleaders find themselves on the horns of a dilemma. tanyev 14 hrs ago #3
Until AI decides Trashman272 13 hrs ago #4
The term "AI" has become shorthand for so many things that it's irresponsible to use it to describe what's happening WhiskeyGrinder 13 hrs ago #5
Do you know more details about the methodology ? I'm no expert here, but I'm guessing this was basically ... eppur_se_muova 12 hrs ago #6
you're right WhiskeyGrinder 12 hrs ago #8
See reply 10. highplainsdem 10 hrs ago #11
Yup. The headline would make people believe they typed "design a vaccine for me" in Claude or something. Oneironaut 12 hrs ago #7
yep it's the kind of work that's been going on for years before "chatgpt" or "claude" were so widely promoted WhiskeyGrinder 12 hrs ago #9
I agree. See reply 10. highplainsdem 10 hrs ago #12
Researchers used all the genetic sequencing data collected for Sarbeco coronaviruses by monitoring programmes around the Celerity 8 hrs ago #14
Testing of the new vaccine started in 2021. They used machine learning to develop the vaccine before that. NOT genAI, highplainsdem 10 hrs ago #10
Thanks for taking the effort to put together a very informative reply ! I've read about things like large-scale surveys eppur_se_muova 10 hrs ago #13
You're very welcome! highplainsdem 7 hrs ago #16
"researchers found no significant side-effects." LudwigPastorius 8 hrs ago #15

EdmondDantes_

(2,228 posts)
2. As someone who gets colds that last 3 weeks, I'm hoping this works
Wed Jun 10, 2026, 07:28 AM
14 hrs ago

But I'm still skeptical given how frequently various respiratory viruses mutate. But then again they are the experts so hopefully they found something key.

WhiskeyGrinder

(27,324 posts)
5. The term "AI" has become shorthand for so many things that it's irresponsible to use it to describe what's happening
Wed Jun 10, 2026, 08:44 AM
13 hrs ago

here, even in a headline.

eppur_se_muova

(42,767 posts)
6. Do you know more details about the methodology ? I'm no expert here, but I'm guessing this was basically ...
Wed Jun 10, 2026, 09:42 AM
12 hrs ago

... "machine learning", which has led to a number of discoveries in the physical sciences, but which is not Large Language Model AI. If anything, it's closer to classical numerical curve-fitting than to "AI" as such.

Oneironaut

(6,345 posts)
7. Yup. The headline would make people believe they typed "design a vaccine for me" in Claude or something.
Wed Jun 10, 2026, 09:47 AM
12 hrs ago

The scientific part of “AI” is not a bs scam, and, is actually helping contribute to our scientific knowledge by doing what computers do well - analyzing data.

WhiskeyGrinder

(27,324 posts)
9. yep it's the kind of work that's been going on for years before "chatgpt" or "claude" were so widely promoted
Wed Jun 10, 2026, 09:49 AM
12 hrs ago

Celerity

(55,176 posts)
14. Researchers used all the genetic sequencing data collected for Sarbeco coronaviruses by monitoring programmes around the
Wed Jun 10, 2026, 01:28 PM
8 hrs ago

globe and then used artificial intelligence to design an antigen, the element within a virus that the immune system learns to attack, with “features common to this whole group of viruses, including ones that haven’t emerged yet”, the scientists said.

It was delivered using a high-pressure jet of liquid that can penetrate the skin, rather than a needle.

snip

highplainsdem

(63,462 posts)
10. Testing of the new vaccine started in 2021. They used machine learning to develop the vaccine before that. NOT genAI,
Wed Jun 10, 2026, 11:58 AM
10 hrs ago

or generative AI, the type of AI we've been hearing the most about for the last 3-1/2 years thanks to ChatGPT, Claude, etc.

AI bros pushing genAI often try to confuse the types of AI and make it appear that genAI is behind scientific and medical advances, but that's rarely the case.

June 2026 Cambridge article mentioning machine learning: https://www.cam.ac.uk/research/news/new-universal-vaccine-technology-could-protect-us-from-future-virus-outbreaks

Journal article on the study: https://www.journalofinfection.com/article/S0163-4453(26)00084-8/fulltext
(DU's software breaks the link above, so you'll have to copy it to the address bar.)

Between December 2021 and September 2023, a total of 39 volunteers were vaccinated.

eppur_se_muova

(42,767 posts)
13. Thanks for taking the effort to put together a very informative reply ! I've read about things like large-scale surveys
Wed Jun 10, 2026, 12:18 PM
10 hrs ago

of archaeological sites, design of enzyme inhibitors, and other "data intensive" investigations -- plus others whose details I don't recall -- benefiting from machine learning. I've slowly come to realize that confusing people on what "AI" really is is probably a deliberate ploy -- machine learning has some real successes to its credit, but LLMs have delivered one boner after another, many of them quite dangerous, even potentially disastrous. Not good for IPOs, I'm sure ! So, dilute/camouflage the bad news with genuine (but not really related) good news, and suddenly AI can be made to look more worthwhile, if you don't look too closely.

I'm still expecting "AI", as it exists in corporate America's marketing departments, to result in huge writeoffs for corps. I've posted an article about that a couple of times.

highplainsdem

(63,462 posts)
16. You're very welcome!
Wed Jun 10, 2026, 03:10 PM
7 hrs ago

We get so many lies and so much hype from the AI bros pushing generative AI. It's important to keep ML's real contributions to science separate from genAI.

I'm not sure what's going to happen with genAI. My hope is that the tremendous waste of time and resources will soon look as misguided as the Dutch tulip mania...but the genAI frenzy is already much more damaging to many aspects of our society, and potentially much more of a financial catastrophe than the tulip mania was. So many people invested in genAI, from business owners to school admins to venture capitalists, have incentives to try to keep hyping AI as long as the bubble is in any way sustainable. And the AI bros have the corrupt and perpetually lying Trump regime behind them.

I found the OP about the article on AI you referred to: https://www.democraticunderground.com/100221221280 .

Their reasoning is similar to Ed Zitron's.

LudwigPastorius

(15,164 posts)
15. "researchers found no significant side-effects."
Wed Jun 10, 2026, 02:17 PM
8 hrs ago

...other than developing a taste for human brains?

jk

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