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mr715

(4,620 posts)
Sun Jun 7, 2026, 01:26 PM Yesterday

My lab applied for a grant to combat screwworm

We are a neurogenetics team that studies mosquitoes.

We hope to find genetic tools to combat screwworm and prevent it from spreading. We've been told if we get the grant, our lab will end up smelling really, really bad.

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My lab applied for a grant to combat screwworm (Original Post) mr715 Yesterday OP
mr715, what is the status of gene drive tech, and might a threat like this ease restrictions? harumph Yesterday #1
We are very careful when working with genetic modifications... mr715 Yesterday #2

harumph

(3,465 posts)
1. mr715, what is the status of gene drive tech, and might a threat like this ease restrictions?
Sun Jun 7, 2026, 01:38 PM
Yesterday

I know some are scared of the technique - but your thoughts? Thank you, Harumph

Understanding this is a result of the new world screwfly - not a virus, even so, my mind goes back to the film HUD with Paul Newman when he encounters some cattle that have contracted Hoof and Mouth and tries to get his father to hide it. I wonder if Texas ranchers will be incentivized to report incidents of screwworm infestations, or just treat it ad hoc and keep it quiet. It wouldn't make any sense to me to hide it - but fuck if I can figure out how these folks think.

mr715

(4,620 posts)
2. We are very careful when working with genetic modifications...
Sun Jun 7, 2026, 01:49 PM
Yesterday

We make sure ours do not get out of the room they are in, much less the building.

I know there are many places doing active population control using gene drive. The mosquito genome is pretty unusual, so it permits some specialized targeting for control measures. Much like we can poison bacteria with antibiotics w/o sideeffects for us because they have different structures than us...

I'll admit to a personal squeamishness at widespread release of organisms that are driving deep evolutionary change. The benefit of making a generation of all male mosquitoes is you don't lose the good stuff mosquitoes do, like pollination and being food for fish and birds. I just don't think we know enough about ecological dynamics to predict what might happen if we reduce the complexity of a system. Perhaps, idk, maybe a skewed male population spends more time asleep and therefore misses the time a particularly cool bird eats...

These are fascinating questions that are getting explored. Not by me, sadly, but still really interesting.

And I'll close with GMOs shouldn't be scary under controlled settings. We've been genetically modifying organisms since 20,000 BCE. It is probably a potent solution to the mosquito problem in the same way that GMOs helped solve food insecurity and allowed a human population of 8-9 billion.

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