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littlemissmartypants

(31,650 posts)
Sat Dec 13, 2025, 02:07 PM Dec 13

...personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer

A tiny trial in New York has shown that personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer, even as sweeping federal cuts now threaten the fragile labs required to produce them.
https://theintellectualistofficial.substack.com/p/a-breakthr...

A tiny trial in New York has shown that personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer, even as sweeping federal cuts now threaten the fragile labs required to produce them.
theintellectualistofficial.substack.com/p/a-breakthr...

The Intellectualist (@theintellectualist.bsky.social) 2025-12-12T16:02:47.110Z


Impeach the Quack (RFK, jr). Take a moment and send a Quack-o-gram to YOUR Congress-critter, today. #StandUpForScience #Purdue #Indiana Only Three (3) dollars! https://act.standupforscience.net/fundraising/send-your-congressperson-a-quackogram-impeach-and-removing-rfk/

Impeach the Quack (RFK, jr). Take a moment and send a Quack-o-gram to YOUR Congress-critter, today. #StandUpForScience #Purdue #Indiana Only Three (3) dollars! act.standupforscience.net/fundraising/...

Greater Lafayette Indivisible ❌ 👑 (@lafayetteindivisible.com) 2025-12-13T15:21:15.217Z
9 replies = new reply since forum marked as read
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...personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer (Original Post) littlemissmartypants Dec 13 OP
Trump and his billionaire buds appear to be in the process of culling the proverbial herd AZJonnie Dec 13 #1
You're giving them too much credit. They're not that deep. littlemissmartypants Dec 13 #2
Okay I'll make it more basic AZJonnie Dec 13 #3
Shame there's no mRNA for brains. Kid Berwyn Dec 13 #4
That's okay Old Crank Dec 13 #5
Pancreatic cancer is known to have a genetic basis, with the pathogenic mutation being dominant. President Carter's... NNadir Dec 13 #6
TY littlemissmartypants Dec 13 #7
Stress is a large factor in causing cancer also. ananda Dec 13 #9
I watched my mother die of that wretched disease. mn9driver Dec 13 #8

AZJonnie

(2,831 posts)
1. Trump and his billionaire buds appear to be in the process of culling the proverbial herd
Sat Dec 13, 2025, 02:53 PM
Dec 13

I suspect it's because of an awareness among them about the combined effects of upcoming catastrophic climate change and the fact that fossil fuels are beginning to get expensive (both money-wise and EROEI-wise) to extract (due to permanent depletion). Thus perhaps they operate under the assumption in not that long, the earth's carrying capacity will be drastically reduced. And I mean like, halved, in span of possibly as short as 20 years. And that this point may be a lot closer than anyone wants to think about, or is willing to admit.

In any event, they certainly seem to be very blasé about the idea of letting Americans die off

littlemissmartypants

(31,650 posts)
2. You're giving them too much credit. They're not that deep.
Sat Dec 13, 2025, 03:40 PM
Dec 13

Characteristics of Psychopaths

1. Aggressive, callous, and cunning
2. Complete absence of conscience and empathy
3. Very adept at manipulating others
4. Willingness to engage in immoral, criminal conduct
5. Willingness to take what they want and do as they please, regardless of who is hurt or wronged
6. Deceptive ability to appear outwardly benevolent
7. Deceptive ability to behave in superficially charming ways to hide purely selfish motives
8. Willingness to use intimidation and violence to control others in order to satisfy their own needs
9. Willingness to intentionally violate the basic inherent human rights of others
10. Complete absence of any sense of guilt or remorse for the harm their actions have caused to others
11. Rationalization of their own immoral behavior
12. Will attempt to lay blame upon someone else for their own conduct
13. Denial, will deny their own wrongdoing outright
14. Utter contemptuousness toward the feelings and desires of their fellow beings
15. Pathological lying, will say anything without any concern for truth to advance their own hidden agendas
16. Ablity to feign [fake] normal human emotions and empathy
17. Distorted sense of the consequences of their actions
18. Total failure to accept any responsibility for their own socially irresponsible ways
19. Strong bellef that they will never be brought to justice for their criminal behavior

AZJonnie

(2,831 posts)
3. Okay I'll make it more basic
Sat Dec 13, 2025, 03:43 PM
Dec 13

"With all these extra people, there's not going to be enough power for our 50,000 Gigawatt Mega-Ultra AI Crypto Data Centers!!!"

Think they could manage a thought that deep?

NNadir

(37,302 posts)
6. Pancreatic cancer is known to have a genetic basis, with the pathogenic mutation being dominant. President Carter's...
Sat Dec 13, 2025, 04:33 PM
Dec 13

...family clearly had it, his three siblings, his father, and his mother, all having died from it. His mother however, lived quite long despite the gene.

It would seem that both his father and mother were heterozygous, since Jimmy himself didn't get the disease, a classic distribution for double heterozygous parents with a dominant gene, 3:1.

This said, personalized medicine is a very, very, very expensive endeavor. I have no doubt that the treatment may work, if in fact, it represents a CRISPR type approach - I've worked on gene expression products - but it will require a lot of individual Nextgen sequencing.

It will probably end up being a treatment for the rich and not available for the poor.

In an ideal world, those with a known familial history of the disease would be able to get the treatment, should it pan out. My experience on this frontier suggests it well may.

That's not going to happen though with a government run by murderous ignoramuses.

ananda

(34,434 posts)
9. Stress is a large factor in causing cancer also.
Sat Dec 13, 2025, 05:30 PM
Dec 13

In my immediate family, two incidents of cancer were
caused by strong outside stressors. Both were cured,
one with chemo, and the other with surgery.

My aunt got pancreatic cancer way late in life and died
of it at age 90.

My uncle and his daughter both got colon cancer and
died of it.

I decided early on that I didn't want to get diabetes
or cancer... I'm very old and except for minor problems,
in very good health. No smoking, no alcohol, and
only organic food... along with exercise and less stress.

There was a famous oncologist in Houston, John Stehlin,
who used to speak about cancer on TV news shows.
He said, in his experience, cancer was mostly the result
of stress.

mn9driver

(4,821 posts)
8. I watched my mother die of that wretched disease.
Sat Dec 13, 2025, 05:19 PM
Dec 13

The space between her diagnosis and her death in early 2007 was only 4 months. I remember helping her pack up and put away Christmas when she stopped for a moment and said, “This is the last time I get to do this.”

These mRNA treatments didn’t exist, but she kept hoping even so.

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